Nuclear Magnetic Resonance (NMR)

1D experiments

¹H and ¹⁹F on high-frequency coil, with a tuneable low-frequency coil to any nucleus frequency between ³¹P and ¹⁵N – typically used for ¹³C, ³¹P ²⁹Si, ²⁷Al, ¹¹B.

A dual-tune mode is available for the high-frequency coil allowing us to carry out proton measurements with fluorine decoupling or vice versa. Furthermore, we can decouple both proton and fluorine simultaneously for ¹³C spectra, simplifying assignments of ¹³C spectra of more complex fluorine containing compounds, or allowing C-F DEPT experiments.

For polymeric samples, T2-filtered experiments can allow analysis of end-groups and residual monomers.

1D NOESY/TOCSY/EXSY

2D Experiments

The standard suite of H-X (X typically ¹³C, ¹⁵N) correlation experiments is available for full characterisation– COSY, HMBC, HMQC, NOESY/ROESY, TOCSY for full characterisations.

For polymeric samples and complex mixtures, 1D & 2D diffusion measurements (DOSY) are available, allowing measurement of diffusion coefficients, estimation of molecular weight distribution, and potentially identification of mixtures.

Our HXMAS solid state probe uses 3.2mm solid sample rotors, which are capable of magic-angle spinning (MAS) up to 22 KHz. Approximately 100 mg of sample is required, however the technique is non-destructive.

1D experiments

Simple MAS experiments for ¹H and ¹⁹F available in single-tune mode, with a tuneable low frequency coil typically used for X = ¹³C, ³¹P, ²⁹Si, ²⁷Al, ²³Na, ⁷Li, ⁷⁹Br, ³⁵Cl.

Cross-polarisation experiments for enhancement of sensitivity of nuclei such as ¹³C, ¹⁵N is available for molecules with protons adjacent to the nuclei of interest.

2D experiments

HETCOR (for H-X heteronuclear correlation) and INADEQUATE (for homonuclear) characterisations are available to be discussed on request.