Engineering solutions for cryopreservation in regenerative medicine –
PhD Supervisor(s): Nick Medcalf and Rob Thomas.
Cryopreservation methods for cells for therapeutic use have the potential to influence the quality and efficacy of the product. The EPSRC Centre for Innovative Manufacturing in Regenerative Medicine has a research theme of reducing variability in product quality, with automation where necessary. New cryopreservation or cold transit materials have emerged that may permit cell-based therapeutics to be transported to the user under chilled conditions. This project will address the preservation step for cell-based therapeutics as a unit operation and will consider how the step may be automated and how it may be scalable and integrated with a machine-based harvesting step.
